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Although the assimilatory metabolism of OSC's like methionine by methionine gamma lyase (mgl) and 3′-phosphoadenosine 5′-phosphate by PAPS Reductase (PAPSR), and sulfite by sulfite reductase (SIR) are common within the microbiome, cysteine-metabolizing enzymes are by far the most expressed and highly conserved genes across nearly all microbiota residing in the human gut-microbiome [113]