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UV radiation increases the production of ROS in melanocytes, leading to oxidative stress that activates melanogenesis through the stimulation of molecules like α-MSH 124
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UBIAD1 is also proposed to directly mediate CoQ synthesis in the Golgi to prevent lipid peroxidation 148 , which would be important as this could potentially provide a source of non-mitochondrial CoQ in the secretory pathway and plasma membrane that is accessible by FSP1
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