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This cascade of oxidative damage to proteins, lipids, and DNA highlights the interconnected pathways through which N₂O affects neural integrity ( 6.2.2 Excitotoxicity N₂O acts as a noncompetitive inhibitor of NMDAR, disrupting their regulatory role in synaptic plasticity, memory, and learning (Poddar and Paul, 2009)
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This effect, as a close interaction with dopamine system functioning, was able to determine an active gut-brain axis or brain-gut axis functioning[2]
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