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[DOI] [PubMed] [Google Scholar] 65.Krogh KA, Wydeven N, Wickman K, Thayer SA
Hydration Complex
Color:30 CT
First, ROS directly modifies ion channels, oxidizing sulfhydryl groups on voltage-gated Na+ channels, resulting in abnormal action potential propagation and contributing to the paradoxical coexistence of pain and numbness (Elafros et al., 2022)