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For biofluid-specific assessment 25 (44.6%) partially matched lumbar CSF and plasma samples were included in the targeted analysis and compared against the full targeted ventricular CSF cohort, irrespective of follow-up availability (34)

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For instance, H3K18la transcriptionally activates VCAM1, which subsequently activates the AKT-mTOR-CXCL1 axis, ultimately provoking EMT and migration of gastric cancer cells and resulting in immunosuppression and unfavorable prognosis