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In individuals carrying the C677T variant, enzyme activity decreased to approximately 67% and 25% for those with one copy (heterozygous) and two copies (homozygous) of the T allele ( MTHFR C677T polymorphism), respectively

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Polycystic Ovarian Syndrome (PCOS) affects more than 10% of all women of reproductive age and is the leading cause of infertility in women under 30